Setton Lab

Our research explores the mechanics and mechanobiology of the musculoskeletal system, focusing on the intervertebral disc, diarthrodial joint and synovium.

Welcome to the Setton Lab at WashU

Our research uses mechanical engineering, materials synthesis, and cell and molecular biology to advance drug- and biomaterial-based musculoskeletal therapies.

Ongoing projects include:

  • Intervertebral disc pain and cell biology
  • Intra-articular drug delivery
  • Biomaterials for intervertebral disc regeneration

Learn more about our research and read our publications.

We are part of the Biomedical Engineering Department in the McKelvey School of Engineering at Washington University in St. Louis. Our lab is located on the third floor of Whitaker Hall on the Danforth campus, which is easily accessible by car, bike, and public transit. We welcome you to join our research efforts.

We are affiliated with WashU’s Center of Regenerative Medicine and Musculoskeletal Research Center.