Principal Investigator
Lori Setton
Professor Setton’s research explores role of mechanical factors in the degeneration and repair of soft tissues of the musculoskeletal system, including the intervertebral disc, articular cartilage, and meniscus. Her work focuses on engineering and evaluating novel materials for tissue regeneration and drug delivery to treat musculoskeletal disease.
Staff
Research analyst
Postdocs
Studies drug diffusion through synovium
Engineers platforms that precondition stem cells
to regenerate the intervertebral disc
PhD Students
Quantitatively assesses collagen morphology
in synovium using SHG microscopy
Functionalizes alginate hydrogels with
cell-adhesive and growth-factor-mimicking
peptides to promote stem cell differentiation
Engineers alginate hydrogels to mimic the
extracellular matrix of primary intervetebral
disc cells
Master’s Students
Studies how encapsulated stem cells
respond to mechanical loading
Uses μCT to explore how high-fat diets
affect the intervertebral disc
Undergraduate Students
Biology and math major