Publications

Link to MyNCBI Bibliography

  • Barcellona MN, Speer JE, Fearing BV, Jing L, Pathak A, Gupta MC, Buchowski JM, Kelly M, Setton LA.  Control of adhesive ligand density for modulation of nucleus pulposus cell phenotype.  Biomaterials.  250, 2020.  More info
  • Fearing BV, Jing L, Barcellona MN, Witte SE, Buchowski JM, Zebala LP, Kelly MP, Luhmann S, Gupta MC, Pathak A, Setton LA. Mechanosensitive transcriptional coactivators MRTF-A and YAP/TAZ regulate nucleus pulpous cell phenotype through cell shapeFASEB J. 33, 2019.  More info
  • Guang Y, McGrath TM, Klug N, Nims R, Shih CC, Bayguinov PO, Guilak F, Pham CTN, Fitzpatrick JAJ, Setton LA.  Combined Experimental Approach and Finite Element Modeling of Small Molecule Transport Through Joint Synovium to Measure Effective Diffusivity.  2019.  More info
  • Leimer EM, Gayoso MG, Jing L, Tang SY, Gupta MC, Setton LA.  Behavioral compensations and neuronal remodeling in a rodent model of chronic intervertebral disc degeneration.  Scientific Reports.  2019, 9 (1). More info
  • Tang R, Jing L, Willard VP, Wu C, Guilak F, Chen J, Setton LA.  Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells.  Stem Cell Research & Therapy. 2018, 9 (1). More info
  • Leimer EM, Tanenbaum LM, Nettles DL, Bell RD, Easley ME, Setton LA, Adams SB.  Amino acid profile of synovial fluid following intra-articular ankle fracture.  Foot & Ankle International.  2018, 39 (10), 1169-1177. More info
  • Fearing BV, Hernandez PA, Setton LA, and Chahine NP.  Mechanotransduction and cell biomechanics of the intervertebral disc.  JOR Spine. 2018, 1(3). More info
  • Mwangi TK, Berke IM, Nieves EH, Bell RD, Adams SB, Setton LA.  Intra-articular clearance of labeled dextrans from naive and arthritic rat knee joints.  J Control Release.  2018, 283:76-83. More info
  • Bridgen DT, Fearing BV, Jing L, Sanchez-Adams J, Cohan MC, Guilak F, Chen J, Setton LA.  Regulation of human nucleus pulposus cells by peptide-coupled substrates.  Acta biomaterialia.  2017; 55:100-108. More info
  • Bowles RD, Setton LA.  Biomaterials for intervertebral disc regeneration and repair.  Biomaterials. 2017; 129:54-67. More info
  • Farhang N, Brunger JM, Stover JD, Thakore PI, Lawrence B, Guilak F, Gersbach CA, Setton LA, Bowles RD.  CRISPR-based epigenome editing of cytokine receptors for the promotion of cell survival and tissue deposition in inflammatory environments.  Tissue Eng. Part A. 2017, 23 (15-16).  More info
  • Bowles RD, Karikari IO, Vanderwerken DN, et al. In vivo luminescent imaging of NF-κB activity and NF-κB-related serum cytokine levels predict pain sensitivities in a rodent model of peripheral neuropathy. Eur J Pain. 2016;20(3):365-76. More info
  • Cucchiarini M, McNulty AL, Mauck RL, Setton LA, Guilak F, Madry H.  Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus.  Osteoarthritis Cartilage.  2016, 24 (8).  More info
  • Leimer EM, Pappan KL, Nettles DL, et al. Lipid profile of human synovial fluid following intra-articular ankle fracture. J Orthop Res. 2016;
  • Adams SB, Setton LA, Bell RD, et al. Inflammatory Cytokines and Matrix Metalloproteinases in the Synovial Fluid After Intra-articular Ankle Fracture. Foot Ankle Int. 2015;36(11):1264-71. More info
  • Mwangi TK, Bowles RD, Tainter DM, Bell RD, Kaplan DL, Setton LA. Synthesis and characterization of silk fibroin microparticles for intra-articular drug delivery. Int J Pharm. 2015;485(1-2):7-14.More info
  • Hwang PY, Jing L, Michael KW, Richardson WJ, Chen J, Setton LA. N-Cadherin-Mediated Signaling Regulates Cell Phenotype for Nucleus Pulposus Cells of the Intervertebral Disc.Cel. Mol. Bioeng. 1–12, doi: 10.1007/s12195-014-0373-4 (2014). More info
  • Kimmerling KA, Furman BD, Mangiapani DS, Moverman MA, Sinclair SM, Huebner JL, Chilkoti A, Kraus VB, Setton LA, Guilak F, Olson SA. Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis. Eur Cell Mater 2015;29:12439; discussion 139–40More info
  • Karikari, IO; Gilchrist, CL; Jing, L; Alcorta, DA; Chen, J; Richardson, WJ; Gabr, MA; Bell, RD; Kelley, MJ; Bagley, CA; Setton, LA(2014).”Molecular characterization of chordoma xenografts generated from a novel primary chordoma cell source and two chordoma cell lines.” Journal of neurosurgery. Spine.21(3): 386- 393  More info
  • Bowles, RD; Mata, BA; Bell, RD; Mwangi, TK; Huebner, JL; Kraus, VB; Setton, LA(2014).”In vivo luminescence imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis.” Arthritis and Rheumatology.66(3): 637- 646  More info
  • Francisco, AT; Hwang, PY; Jeong, CG; Jing, L; Chen, J; Setton, LA(2014).”Photocrosslinkable laminin-functionalized polyethylene glycol hydrogel for intervertebral disc regeneration.” Acta Biomaterialia.10(3): 1102- 1111  More info
  • Hwang, PY; Chen, J; Jing, L; Hoffman, BD; Setton, LA(2014).”The role of extracellular matrix elasticity and composition in regulating the nucleus pulposus cell phenotype in the intervertebral disc: a narrative review.” Journal of Biomechanical Engineering.136(2): 021010  More info
  • Evans, CH; Kraus, VB; Setton, LA(2014).”Progress in intra-articular therapy.” Nature Reviews Rheumatology.10(1): 11- 22  More info
  • Jeong, CG; Francisco, AT; Niu, Z; Mancino, RL; Craig, SL; Setton, LA(2014).”Screening of hyaluronic acid-poly(ethylene glycol) composite hydrogels to support intervertebral disc cell biosynthesis using artificial neural network analysis” Acta Biomaterialia.10(8): 3421- 3430  More info
  • Bowles, RD; Masuda, K; Bonassar, L(2013).”Tissue Engineering for Regeneration and Replacement of the Intervertebral Disc” .: 1223- 1251  More info
  • Sinclair, SM; Bhattacharyya, J; McDaniel, JR; Gooden, DM; Gopalaswamy, R; Chilkoti, A; Setton, LA(2013).”A genetically engineered thermally responsive sustained release curcumin depot to treat neuroinflammation.” Journal of Controlled Release.171(1): 38- 47  More info
  • Francisco, AT; Mancino, RJ; Bowles, RD; Brunger, JM; Tainter, DM; Chen, YT; Richardson, WJ; Guilak, F; Setton, LA(2013).”Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration.” Biomaterials.34(30): 7381- 7388  More info
  • Bowles, RD; Karikari, IO; Riebe, KJ; Sempowski, GD; Setton, LA(2013).”IN VIVO IMAGING OF NF-kappa B ACTIVITY AND CORRELATION TO PAIN IN A MODEL OF RADICULOPATHY” Osteoarthritis and Cartilage.21: S59- S60  More info
  • Bowles, RD; Mata, BA; Mwangi, TK; Palmer, GM; Setton, LA(2013).”IN VIVO IMAGING OF NF-kappa B ACTIVITY AND CORRELATION TO PAIN IN A MODEL OF INFLAMMATORY ARTHRITIS” Osteoarthritis and Cartilage.21: S266- S267  More info
  • Francisco, AT; Mancino, RJ; Brunger, JM; Bowles, RD; Guilak, F; Setton, LA(2013).”INJECTABLE LAMININ-FUNCTIONALIZED HYDROGEL FOR CELL DELIVERY TO THE INTERVERTEBRAL DISC” Osteoarthritis and Cartilage.21: S278- S279  More info
  • Kimmerling, KA; Furman, BD; Mangiapani, DS; Moverman, MA; Sinclair, SM; Huebner, JL; Kraus, VB; Setton, LA; Guilak, F; Olson, SA(2013).”PROLONGED LOCAL DELIVERY OF IL-1RA PREVENTS POST-TRAUMATIC ARTHRITIS IN MICE” Osteoarthritis and Cartilage.21: S30- S31  More info
  • Sinclair, SM; Bhattacharyya, J; Little, D; Bowles, RD; Gooden, DM; Toone, EJ; Chilkoti, A; Setton, LA(2013).”PHARMACOKINETICS OF A THERMALLY RESPONSIVE CURCUMIN CONJUGATE FOR LOCAL ANTAGONISM OF NEUROINFLAMMATION IN DISC HERNIATION” Osteoarthritis and Cartilage.21: S292- S293  More info
  • Tainter, D; Bell, R; Nettles, DL; Setton, LA; Parekh, SG; Jr, ASB(2013).”GLUTAMATE IS ELEVATED IN PATHOLOGIC POSTERIOR TIBIAL TENDONS OF PATIENTS WITH POSTERIOR TIBIAL TENDON DYSFUNCTION” Osteoarthritis and Cartilage.21: S261- S261  More info
  • Adams, SB; Setton, LA; Nettles, DL(2013).”The role of metabolomics in osteoarthritis research.” The Journal of the American Academy of Orthopaedic Surgeons.21(1): 63- 64  More info
  • Bridgen, DT; Gilchrist, CL; Richardson, WJ; Isaacs, RE; Brown, CR; Yang, KL; Chen, J; Setton, LA(2013).”Integrin-mediated interactions with extracellular matrix proteins for nucleus pulposus cells of the human intervertebral disc” Journal of Orthopaedic Research.31(10): 1661- 1667  More info
  • Chen, J; Lee, EJ; Jing, L; Christoforou, N; Leong, KW; Setton, LA(2013).”Differentiation of mouse induced pluripotent stem cells (iPSCs) into nucleus pulposus-like cells in vitro.” PloS one.8(9): e75548 More info
  • Chon, BH; Lee, EJ; Jing, L; Setton, LA; Chen, J(2013).”Human umbilical cord mesenchymal stromal cells exhibit immature nucleus pulposus cell phenotype in a laminin-rich pseudo-three-dimensional culture system” Stem Cell Research and Therapy.4(5)  More info
  • Jing, L; So, S; Lim, SW; Richardson, WJ; Fitch, RD; Setton, LA; Chen, J(2012).”Differential expression of galectin-1 and its interactions with cells and laminins in the intervertebral disc.” Journal of Orthopaedic Research.30(12): 1923- 1931  More info
  • Setton, LA; Yin, FC; Margulies, SS; Sakiyama-Elbert, SE; Beizer, D(2012).”Getting your research out there: open access & more.” Annals of Biomedical Engineering.40(12): 2503- 2504  More info
  • Adams, SB; Setton, LA; Kensicki, E; Bolognesi, MP; Toth, AP; Nettles, DL(2012).”Global metabolic profiling of human osteoarthritic synovium.” Osteoarthritis and Cartilage.20(1): 64- 67  More info
  • Allen, KD; Mata, BA; Gabr, MA; Huebner, JL; Adams, SB; Kraus, VB; Schmitt, DO; Setton, LA(2012).”Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis.” Arthritis Research and Therapy.14(2): R78  More info
  • Francisco, AT; Mancino, RJ; Jeong, CG; Karikari, IO; Bowles, RD; Craig, SL; Setton, LA(2012).”Injectable and photocrosslinkable laminin functionalized biomaterials for intervertebral disc regeneration” ASME 2012 Summer Bioengineering Conference, SBC 2012.: 1145- 1146  More info
  • Hwang, PY; Allen, KD; Shamji, MF; Jing, L; Mata, BA; Gabr, MA; Huebner, JL; Kraus, VB; Richardson, WJ; Setton, LA(2012).”Changes in midbrain pain receptor expression, gait and behavioral sensitivity in a rat model of radiculopathy.” Open Orthopaedics Journal.6: 383- 391  More info
  • Hwang, PY; Gilchrist, CL; Francisco, AT; Chen, J; Setton, LA(2012).”Cell morphology and migration of nucleus pulposus cells depends on substrate stiffness and ligand” ASME 2012 Summer Bioengineering Conference, SBC 2012.: 1205- 1206  More info
  • Shamji, MF; Hwang, P; Allen, K; Gabr, M; Jing, L; Chen, J; Richardson, WJ; Setton, LA(2011).”Midbrain Neurotransmitter Receptor Expression and Descending Supraspinal Control of Nociception and Pain Behavior in Radiculopathy” Journal of neurosurgery.115(2): A421- A421  More info
  • Sinclair, SM; Shamji, MF; Chen, J; Jing, L; Richardson, WJ; Brown, CR; Fitch, RD; Setton, LA(2011).”Attenuation of inflammatory events in human intervertebral disc cells with a tumor necrosis factor antagonist.” Spine.36(15): 1190- 1196  More info
  • Allen, KD; Adams, SB; Mata, BA; Shamji, MF; Gouze, E; Jing, L; Nettles, DL; Latt, LD; Setton, LA(2011).”Gait and behavior in an IL1β-mediated model of rat knee arthritis and effects of an IL1 antagonist.” Journal of Orthopaedic Research.29(5): 694- 703  More info
  • Cao, L; Guilak, F; Setton, LA(2011).”Three-dimensional finite element modeling of pericellular matrix and cell mechanics in the nucleus pulposus of the intervertebral disk based on in situ morphology.” Biomechanics and Modeling in Mechanobiology.10(1): 1- 10  More info
  • Gabr, MA; Jing, L; Helbling, AR; Sinclair, SM; Allen, KD; Shamji, MF; Richardson, WJ; Fitch, RD; Setton, LA; Chen, J(2011).”Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells.” Journal of Orthopaedic Research.29(1): 1- 7  More info
  • Allen, KD; Shamji, MF; Mata, BA; Gabr, MA; Sinclair, SM; Schmitt, DO; Richardson, WJ; Setton, LA(2011).”Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonism.” Arthritis Research and Therapy.13(4): R137  More info
  • Gilchrist, CL; Darling, EM; Chen, J; Setton, LA(2011).”Extracellular matrix ligand and stiffness modulate immature nucleus pulposus cell-cell interactions.” PloS one.6(11): e27170  More info
  • Gilchrist, CL; Francisco, AT; Plopper, GE; Chen, J; Setton, LA(2011).”Nucleus pulposus cell-matrix interactions with laminins.” European cells & materials.21: 523- 532  More info
  • Nettles, DL; Chilkoti, A; Setton, LA(2010).”Applications of elastin-like polypeptides in tissue engineering.” Advanced Drug Delivery Reviews.62(15): 1479- 1485  More info
  • Shamji, MF; Allen, KD; Gabr, M; Sinclair, M; Mata, B; Nettles, DL; Chen, J; Jing, L; Richardson, WJ; Setton, LA(2010).”Local and Sustained Anticytokine Delivery Reverses Gait and Sensory Changes in Experimental Disc Herniation Radiculopathy” Journal of neurosurgery.113(2): A436- A436  More info
  • Costello, KE; Guilak, F; Setton, LA; Griffin, TM(2010).”Locomotor activity and gait in aged mice deficient for type IX collagen.” Journal of applied physiology (Bethesda, Md. : 1985).109(1): 211- 218 More info
  • Shamji, MF; Setton, LA; Jarvis, W; So, S; Chen, J; Jing, L; Bullock, R; Isaacs, RE; Brown, C; Richardson, WJ(2010).”Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues.” Arthritis and Rheumatism.62(7): 1974- 1982  More info
  • Allen, KD; Adams, SB; Setton, LA(2010).”Evaluating intra-articular drug delivery for the treatment of osteoarthritis in a rat model.” Tissue Engineering, Part B, Reviews.16(1): 81- 92  More info
  • Nettles, DL; Haider, MA; Chilkoti, A; Setton, LA(2010).”Neural network analysis identifies scaffold properties necessary for in vitro chondrogenesis in elastin-like polypeptide biopolymer scaffolds.” Tissue Engineering, Part A.16(1): 11- 20  More info
  • Griffin, TM; Fermor, B; Huebner, JL; Kraus, VB; Rodriguiz, RM; Wetsel, WC; Cao, L; Setton, LA; Guilak, F(2010).”Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice.” Arthritis Research and Therapy.12(4): R130  More info
  • Shamji, MF; Hwang, P; Bullock, RW; Adams, SB; Nettles, DL; Setton, LA(2010).”Release and activity of anti-TNFα therapeutics from injectable Chitosan preparations for local drug delivery (Journal of Biomedical Materials Research Part B: Applied Biomaterials (2009) (321) DOI: 10.1002/jbm.b.31576)” Journal of Biomedical Materials Research Part B: Applied Biomaterials.92(1): 287-  More info
  • Cao, L; Guilak, F; Setton, LA(2009).”Pericellular Matrix Mechanics in the Anulus Fibrosus Predicted by a Three-Dimensional Finite Element Model and In Situ Morphology.” Cellular and Molecular Bioengineering.2(3): 306- 319  More info
  • Allen, KD; Griffin, TM; Rodriguiz, RM; Wetsel, WC; Kraus, VB; Huebner, JL; Boyd, LM; Setton, LA(2009).”Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen.” Arthritis and Rheumatism.60(9): 2684- 2693  More info
  • Mow, VC; Michael Lai, W; Setton, LA; Gu, W; Yao, H; Wan, LQ; Lu, XL(2009).”Discussion: “On the Thermodynamical Admissibility of the Triphasic Theory of Charged Hydrated Tissues” (Huyghe, J. M., Wilson, W., and Malakpoor, K., ASME J. Biomech. Eng., 2009, 131, p. 044504).” Journal of Biomechanical Engineering.131(9): 095501  More info
  • Nettles, DL; Chilkoti, A; Setton, LA(2009).”Early metabolite levels predict long-term matrix accumulation for chondrocytes in elastin-like polypeptide biopolymer scaffolds.” Tissue Engineering, Part A.15(8): 2113- 2121  More info
  • Adams, SB; Shamji, MF; Nettles, DL; Hwang, P; Setton, LA(2009).”Sustained release of antibiotics from injectable and thermally responsive polypeptide depots.” Journal of Biomedical Materials Research Part B: Applied Biomaterials.90(1): 67- 74  More info
  • Christensen, T; Amiram, M; Dagher, S; Trabbic-Carlson, K; Shamji, MF; Setton, LA; Chilkoti, A(2009).”Fusion order controls expression level and activity of elastin-like polypeptide fusion proteins.” Protein Science.18(7): 1377- 1387  More info
  • Jr, ASB; Shamji, MF; Nettles, DL; Hwang, P; Setton, LA(2009).”Sustained Release of Antibiotics From Injectable and Thermally Responsive Polypeptide Depots” Journal of Biomedical Materials Research Part B: Applied Biomaterials.90B(1): 67- 74  More info
  • Shamji, MF; Hwang, P; Bullock, RW; Adams, SB; Nettles, DL; Setton, LA(2009).”Release and Activity of Anti-TNF alpha Therapeutics From Injectable Chitosan Preparations for Local Drug Delivery” Journal of Biomedical Materials Research Part B: Applied Biomaterials.90B(1): 319- 326  More info
  • Shamji, MF; Allen, KD; So, S; Jing, L; Adams, SB; Schuh, R; Huebner, J; Kraus, VB; Friedman, AH; Setton, LA; Richardson, WJ(2009).”Gait abnormalities and inflammatory cytokines in an autologous nucleus pulposus model of radiculopathy.” Spine.34(7): 648- 654  More info
  • Chen, J; Jing, L; Gilchrist, CL; Richardson, WJ; Fitch, RD; Setton, LA(2009).”Expression of laminin isoforms, receptors, and binding proteins unique to nucleus pulposus cells of immature intervertebral disc.” Connective Tissue Research (Informa).50(5): 294- 306  More info
  • Shamji, MF; Chen, J; Friedman, AH; Richardson, WJ; Chilkoti, A; Setton, LA(2008).”Synthesis and characterization of a thermally-responsive tumor necrosis factor antagonist.” Journal of Controlled Release.129(3): 179- 186  More info
  • Shamji, MF; Jing, L; Chen, J; Hwang, P; Ghodsizadeh, O; Friedman, AH; Richardson, WJ; Setton, LA(2008).”Treatment of neuroinflammation by soluble tumor necrosis factor receptor Type II fused to a thermally responsive carrier.” Journal of neurosurgery. Spine.9(2): 221- 228  More info
  • Upton, ML; Gilchrist, CL; Guilak, F; Setton, LA(2008).”Transfer of macroscale tissue strain to microscale cell regions in the deformed meniscus.” Biophysical Journal.95(4): 2116- 2124  More info
  • Nettles, DL; Kitaoka, K; Hanson, NA; Flahiff, CM; Mata, BA; Hsu, EW; Chilkoti, A; Setton, LA(2008).”In situ crosslinking elastin-like polypeptide gels for application to articular cartilage repair in a goat osteochondral defect model.” Tissue Engineering, Part A.14(7): 1133- 1140  More info
  • Shamji, MF; Whitlatch, L; Friedman, AH; Richardson, WJ; Chilkoti, A; Setton, LA(2008).”An injectable and in situ-gelling biopolymer for sustained drug release following perineural administration.” Spine.33(7): 748- 754  More info
  • Boyd, LM; Richardson, WJ; Allen, KD; Flahiff, C; Jing, L; Li, Y; Chen, J; Setton, LA(2008).”Early-onset degeneration of the intervertebral disc and vertebral end plate in mice deficient in type IX collagen.” Arthritis and Rheumatism.58(1): 164- 171  More info
  • Lim, DW; Nettles, DL; Setton, LA; Chilkoti, A(2008).”In situ cross-linking of elastin-like polypeptide block copolymers for tissue repair.” Biomacromolecules.9(1): 222- 230  More info
  • Setton, L(2008).”Polymer therapeutics: reservoir drugs.” Nature Materials.7(3): 172- 174  More info
  • Shamji, MF; Betre, H; Kraus, VB; Chen, J; Chilkoti, A; Pichika, R; Masuda, K; Setton, LA(2007).”Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic.” Arthritis and Rheumatism.56(11): 3650- 3661  More info
  • Cao, L; Guilak, F; Setton, LA(2007).”Three-dimensional morphology of the pericellular matrix of intervertebral disc cells in the rat.” Journal of Anatomy.211(4): 444- 452  More info
  • Roberts, SK; Chilkoti, A; Setton, LA(2007).”Multifunctional thermally transitioning oligopeptides prepared by ring-opening metathesis polymerization.” Biomacromolecules.8(8): 2618- 2621  More info
  • Gilchrist, CL; Chen, J; Richardson, WJ; Loeser, RF; Setton, LA(2007).”Functional integrin subunits regulating cell-matrix interactions in the intervertebral disc.” Journal of Orthopaedic Research.25(6): 829- 840  More info
  • Lim, DW; Nettles, DL; Setton, LA; Chilkoti, A(2007).”Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl)phosphines in aqueous solution.” Biomacromolecules.8(5): 1463- 1470  More info
  • Choi, JB; Youn, I; Cao, L; Leddy, HA; Gilchrist, CL; Setton, LA; Guilak, F(2007).”Zonal changes in the three-dimensional morphology of the chondron under compression: the relationship among cellular, pericellular, and extracellular deformation in articular cartilage.” Journal of Biomechanics.40(12): 2596- 2603  More info
  • Gilchrist, CL; Witvoet-Braam, SW; Guilak, F; Setton, LA(2007).”Measurement of intracellular strain on deformable substrates with texture correlation.” Journal of Biomechanics.40(4): 786- 794  More info
  • Setton, LA; Bonassar, LJ; Masuda, K(2007).”Regeneration and replacement of the intervertebral disc” .: 877- 896  More info
  • Betre, H; Liu, W; Zalutsky, MR; Chilkoti, A; Kraus, VB; Setton, LA(2006).”A thermally responsive biopolymer for intra-articular drug delivery.” Journal of Controlled Release.115(2): 175- 182  More info
  • Cao, L; Youn, I; Guilak, F; Setton, LA(2006).”Compressive properties of mouse articular cartilage determined in a novel micro-indentation test method and biphasic finite element model.” Journal of Biomechanical Engineering.128(5): 766- 771  More info
  • Hu, K; Xu, L; Cao, L; Flahiff, CM; Brussiau, J; Ho, K; Setton, LA; Youn, I; Guilak, F; Olsen, BR; Li, Y(2006).”Pathogenesis of osteoarthritis-like changes in the joints of mice deficient in type IX collagen.” Arthritis and Rheumatism.54(9): 2891- 2900  More info
  • Youn, I; Choi, JB; Cao, L; Setton, LA; Guilak, F(2006).”Zonal variations in the three-dimensional morphology of the chondron measured in situ using confocal microscopy.” Osteoarthritis and Cartilage.14(9): 889- 897  More info
  • Chen, J; Yan, W; Setton, LA(2006).”Molecular phenotypes of notochordal cells purified from immature nucleus pulposus.” European Spine Journal.15 Suppl 3: S303- S311  More info
  • Upton, ML; Chen, J; Setton, LA(2006).”Region-specific constitutive gene expression in the adult porcine meniscus.” Journal of Orthopaedic Research.24(7): 1562- 1570  More info
  • Haider, MA; Schugart, RC; Setton, LA; Guilak, F(2006).”A mechano-chemical model for the passive swelling response of an isolated chondron under osmotic loading.” Biomechanics and Modeling in Mechanobiology.5(2-3): 160- 171  More info
  • Upton, ML; Guilak, F; Laursen, TA; Setton, LA(2006).”Finite element modeling predictions of region-specific cell-matrix mechanics in the meniscus.” Biomechanics and Modeling in Mechanobiology.5(2-3): 140- 149  More info
  • Andersson, GB; An, HS; Oegema, TR; Setton, LA(2006).”Intervertebral disc degeneration. Summary of an AAOS/NIH/ORS workshop, September 2005.” The Journal of Bone and Joint Surgery.88(4): 895- 899  More info
  • Andersson, GB; An, HS; Oegema, TR; Setton, LA(2006).”Directions for future research.” The Journal of Bone and Joint Surgery.88 Suppl 2: 110- 114  More info
  • Guilak, F; Alexopoulos, LG; Upton, ML; Youn, I; Choi, JB; Cao, L; Setton, LA; Haider, MA(2006).”The pericellular matrix as a transducer of biomechanical and biochemical signals in articular cartilage.” Annals of the New York Academy of Sciences.1068: 498- 512  More info
  • Setton, LA; Chen, J(2006).”Mechanobiology of the intervertebral disc and relevance to disc degeneration.” The Journal of Bone and Joint Surgery.88 Suppl 2: 52- 57  More info
  • Hyun, J; Chen, J; Setton, LA; Chilkoti, A(2006).”Patterning cells in highly deformable microstructures: effect of plastic deformation of substrate on cellular phenotype and gene expression.” Biomaterials.27(8): 1444- 1451  More info
  • Ong, SR; Trabbic-Carlson, KA; Nettles, DL; Lim, DW; Chilkoti, A; Setton, LA(2006).”Epitope tagging for tracking elastin-like polypeptides.” Biomaterials.27(9): 1930- 1935  More info
  • Betre, H; Ong, SR; Guilak, F; Chilkoti, A; Fermor, B; Setton, LA(2006).”Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide.” Biomaterials.27(1): 91- 99  More info
  • Söntjens, SH; Nettles, DL; Carnahan, MA; Setton, LA; Grinstaff, MW(2006).”Biodendrimer-based hydrogel scaffolds for cartilage tissue repair.” Biomacromolecules.7(1): 310- 316  More info
  • Andersson, GBJ; An, HS; Jr, TRO; Setton, LA(2006).”Intervertebral disc degeneration: Introduction” The Journal of Bone and Joint Surgery.88(SUPPL. 2): 1- 2  More info
  • Andersson, GBJ; An, HS; Oegema, TR; Setton, LA(2006).”Intervertebral disc degenera – AAOS/NIH/ORS workshop – September 15-18, 2005 – Introduction” The Journal of Bone and Joint Surgery.88A: 1- 2  More info
  • Chen, J; Yan, W; Setton, LA(2006).”Molecular phenotypes of notochordal cells purified from immature nucleus pulposus” European Spine Journal.15(SUPPL. 3): S303- S311  More info
  • Setton, LA; Chen, J(2006).”Mechanobiology of the intervertebral disc and relevance to disc degeneration” The Journal of Bone and Joint Surgery.88(SUPPL. 2): 52- 57  More info
  • Upton, ML; Hennerbichler, A; Fermor, B; Guilak, F; Weinberg, JB; Setton, LA(2006).”Biaxial strain effects on cells from the inner and outer regions of the meniscus.” Connective Tissue Research (Informa).47(4): 207- 214  More info
  • McHale, MK; Setton, LA; Chilkoti, A(2005).”Synthesis and in vitro evaluation of enzymatically cross-linked elastin-like polypeptide gels for cartilaginous tissue repair.” Tissue Engineering.11(11-12): 1768- 1779  More info
  • Guilak, F; Alexopoulos, LG; Haider, MA; Ting-Beall, HP; Setton, LA(2005).”Zonal uniformity in mechanical properties of the chondrocyte pericellular matrix: micropipette aspiration of canine chondrons isolated by cartilage homogenization.” Annals of Biomedical Engineering.33(10): 1312- 1318  More info
  • Boyd, LM; Richardson, WJ; Chen, J; Kraus, VB; Tewari, A; Setton, LA(2005).”Osmolarity regulates gene expression in intervertebral disc cells determined by gene array and real-time quantitative RT-PCR.” Annals of Biomedical Engineering.33(8): 1071- 1077  More info
  • Alexopoulos, LG; Setton, LA; Guilak, F(2005).”The biomechanical role of the chondrocyte pericellular matrix in articular cartilage.” Acta Biomaterialia.1(3): 317- 325  More info
  • Alexopoulos, LG; Williams, GM; Upton, ML; Setton, LA; Guilak, F(2005).”Osteoarthritic changes in the biphasic mechanical properties of the chondrocyte pericellular matrix in articular cartilage.” Journal of Biomechanics.38(3): 509- 517  More info
  • Cao, L; Youn, I; Li, Y; Guilak, F; Olsen, BR; Setton, LA(2005).”Biphasic micro-indentation testing of mouse articular cartilage reveals functional changes in a type IX collagen knockout model of osteoarthritis” Proceedings of the 2005 Summer Bioengineering Conference.2005: 233- 234  More info
  • Chen, J; Yan, W; Setton, LA(2005).”Molecular phenotypes of notochordal cells purified from nucleus pulposus via fluorescence-activated cell sorting” European cells & materials.10(SUPPL.3): 16-  More info
  • Haider, MA; Nettles, DL; Trabbic-Carlson, K; Chilkoti, A; Setton, LA(2005).”Predictive modeling of polypeptide hydrogel mechanical properties for cartilage repair using artificial neural networks” Proceedings of the 2005 Summer Bioengineering Conference.2005: 633- 634  More info
  • Haider, MA; Schugart, RC; Setton, LA; Guilak, F(2005).”A mechano-chemical model for osmotic loading of an isolated chondron” Proceedings of the 2005 Summer Bioengineering Conference.2005: 613- 614  More info
  • Setton, LA(2005).”Cell mechanics and mechanobiology in the intervertebral disc” European cells & materials.10(SUPPL.3): 22-  More info
  • Upton, ML; Laursen, TA; Guilak, F; Setton, LA(2005).”Finite element modeling of region-specific cell-matrix interactions in the meniscus” Proceedings of the 2005 Summer Bioengineering Conference.2005: 229- 230  More info
  • An, HS; Anderson, PA; Haughton, VM; Iatridis, JC; Kang, JD; Lotz, JC; Natarajan, RN; Oegema, TR; Roughley, P; Setton, LA; Urban, JP; Videman, T; Andersson, GB; Weinstein, JN(2004).”Introduction: disc degeneration: summary.” Spine.29(23): 2677- 2678  More info
  • Setton, LA; Chen, J(2004).”Cell mechanics and mechanobiology in the intervertebral disc.” Spine.29(23): 2710- 2723  More info
  • Boyd, LM; Chen, J; Kraus, VB; Setton, LA(2004).”Conditioned medium differentially regulates matrix protein gene expression in cells of the intervertebral disc.” Spine.29(20): 2217- 2222  More info
  • Sontjens, SHM; Nettles, DL; Carnahan, MA; Setton, LA; Grinstaff, MW(2004).”Novel hydrogel scaffolds for cartilage tissue repair, using photocrosslinkable biodendrimers.” ACS National Meeting Book of Abstracts.228: U443- U443  More info
  • Guilak, F; Fermor, B; Keefe, FJ; Kraus, VB; Olson, SA; Pisetsky, DS; Setton, LA; Weinberg, JB(2004).”The role of biomechanics and inflammation in cartilage injury and repair.” Clinical Orthopaedics and Related Research ®.(423): 17- 26  More info
  • Kraus, VB; Huebner, JL; Stabler, T; Flahiff, CM; Setton, LA; Fink, C; Vilim, V; Clark, AG(2004).”Ascorbic acid increases the severity of spontaneous knee osteoarthritis in a guinea pig model.” Arthritis and Rheumatism.50(6): 1822- 1831  More info
  • Nettles, DL; Richardson, WJ; Setton, LA(2004).”Integrin expression in cells of the intervertebral disc.” Journal of Anatomy.204(6): 515- 520  More info
  • Flahiff, CM; Kraus, VB; Huebner, JL; Setton, LA(2004).”Cartilage mechanics in the guinea pig model of osteoarthritis studied with an osmotic loading method.” Osteoarthritis and Cartilage.12(5): 383- 388 More info
  • Gilchrist, CL; Xia, JQ; Setton, LA; Hsu, EW(2004).”High-resolution determination of soft tissue deformations using MRI and first-order texture correlation.” IEEE Transactions on Medical Imaging.23(5): 546- 553  More info
  • Nettles, DL; Vail, TP; Morgan, MT; Grinstaff, MW; Setton, LA(2004).”Photocrosslinkable hyaluronan as a scaffold for articular cartilage repair.” Annals of Biomedical Engineering.32(3): 391- 397  More info
  • Chen, J; Yan, W; Setton, LA(2004).”Static compression induces zonal-specific changes in gene expression for extracellular matrix and cytoskeletal proteins in intervertebral disc cells in vitro.” Matrix Biology.22(7): 573- 583  More info
  • Setton, LA; Chen, J(2004).”Intervertebral disc cell mechanics and biological responses to load” Current Opinion in Orthopaedics.15(5): 331- 340  More info
  • Sontjens, SHM; Nettles, DL; Carnahan, MA; Setton, LA; Grinstaff, MW; medimond, (2004).”Photocrosslinkable biodendrimer-based hydrogel scaffolds for cartilage tissue repair” PROCEEDINGS OF THE 5TH SYMPOSIUM OF THE INTERNATIONAL CARTILAGE REPAIR SOCIETY – ICRS.: 49- 54  More info
  • Upton, ML; Chen, J; Guilak, F; Setton, LA(2003).”Differential effects of static and dynamic compression on meniscal cell gene expression.” Journal of Orthopaedic Research.21(6): 963- 969 More info
  • Xu, L; Flahiff, CM; Waldman, BA; Wu, D; Olsen, BR; Setton, LA; Li, Y(2003).”Osteoarthritis-like changes and decreased mechanical function of articular cartilage in the joints of mice with the chondrodysplasia gene (cho).” Arthritis and Rheumatism.48(9): 2509- 2518  More info
  • Trabbic-Carlson, K; Setton, LA; Chilkoti, A(2003).”Swelling and mechanical behaviors of chemically cross-linked hydrogels of elastin-like polypeptides.” Biomacromolecules.4(3): 572- 580  More info
  • Baer, AE; Laursen, TA; Guilak, F; Setton, LA(2003).”The micromechanical environment of intervertebral disc cells determined by a finite deformation, anisotropic, and biphasic finite element model.” Journal of Biomechanical Engineering.125(1): 1- 11  More info
  • Guilak, F; Setton, LA(2003).”Functional tissue engineering and the role of biomechanical signaling in articular cartilage repair” FUNCTIONAL TISSUE ENGINEERING.: 277- 290  More info
  • Betre, H; Setton, LA; Meyer, DE; Chilkoti, A(2002).”Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair.” Biomacromolecules.3(5): 910- 916  More info
  • Flahiff, CM; Narmoneva, DA; Huebner, JL; Kraus, VB; Guilak, F; Setton, LA(2002).”Osmotic loading to determine the intrinsic material properties of guinea pig knee cartilage.” Journal of Biomechanics.35(9): 1285- 1290  More info
  • Wyland, DJ; Guilak, F; Elliott, DM; Setton, LA; Vail, TP(2002).”Chondropathy after meniscal tear or partial meniscectomy in a canine model.” Journal of Orthopaedic Research.20(5): 996- 1002  More info
  • LeRoux, MA; Setton, LA(2002).”Experimental and biphasic FEM determinations of the material properties and hydraulic permeability of the meniscus in tension.” Journal of Biomechanical Engineering.124(3): 315- 321  More info
  • Chen, J; Baer, AE; Paik, PY; Yan, W; Setton, LA(2002).”Matrix protein gene expression in intervertebral disc cells subjected to altered osmolarity.” Biochemical and Biophysical Research Communications.293(3): 932- 938  More info
  • Elliott, DM; Narmoneva, DA; Setton, LA(2002).”Direct measurement of the Poisson’s ratio of human patella cartilage in tension.” Journal of Biomechanical Engineering.124(2): 223- 228  More info
  • Elliott, DM; Jones, R; Setton, LA; Scully, SP; Vail, TP; Guilak, F(2002).”Joint degeneration following meniscal allograft transplantation in a canine model: mechanical properties and semiquantitative histology of articular cartilage.” Knee Surgery, Sports Traumatology, Arthroscopy.10(2): 109- 118  More info
  • Narmoneva, DA; Cheung, HS; Wang, JY; Howell, DS; Setton, LA(2002).”Altered swelling behavior of femoral cartilage following joint immobilization in a canine model.” Journal of Orthopaedic Research.20(1): 83- 91  More info
  • Betre, H; Chilkoti, A; Setton, LA(2002).”A two-step chondrocyte recovery system based on thermally sensitive elastin-like polypeptide scaffolds for cartilage tissue engineering” Annual International Conference of the IEEE Engineering in Medicine and Biology – Proceedings.1: 829- 830  More info
  • Meng, XN; LeRoux, MA; Laursen, TA; Setton, LA(2002).”A nonlinear finite element formulation for axisymmetric torsion of biphasic materials” International Journal of Solids and Structures.39(4): 879- 895  More info
  • Upton, ML; Chen, J; Guilak, F; Setton, LA(2002).”Static compression inhibits matrix protein gene expression and increases collagenase gene expression in the meniscus” Annual International Conference of the IEEE Engineering in Medicine and Biology – Proceedings.1: 438- 439  More info
  • Narmoneva, DA; Wang, JY; Setton, LA(2001).”A noncontacting method for material property determination for articular cartilage from osmotic loading.” Biophysical Journal.81(6): 3066- 3076 More info
  • Leroux, MA; Cheung, HS; Bau, JL; Wang, JY; Howell, DS; Setton, LA(2001).”Altered mechanics and histomorphometry of canine tibial cartilage following joint immobilization.” Osteoarthritis and Cartilage.9(7): 633- 640  More info
  • Wang, JY; Baer, AE; Kraus, VB; Setton, LA(2001).”Intervertebral disc cells exhibit differences in gene expression in alginate and monolayer culture.” Spine.26(16): 1747- 1751  More info
  • Elliott, DM; Setton, LA(2001).”Anisotropic and inhomogeneous tensile behavior of the human anulus fibrosus: experimental measurement and material model predictions.” Journal of Biomechanical Engineering.123(3): 256- 263  More info
  • Baer, AE; Wang, JY; Kraus, VB; Setton, LA(2001).”Collagen gene expression and mechanical properties of intervertebral disc cell-alginate cultures.” Journal of Orthopaedic Research.19(1): 2- 10 More info
  • Baer, AE; Grinstaff, MW; Smeds, KA; Boyd, LM; Setton, LA(2001).”Nonlinear finite element modeling of cell mechanical environment in hyorogels for intervertebral disc repair” American Society of Mechanical Engineerings, Bioengineering Division (Publication) BED.50: 113- 114  More info
  • Baer, AE; Laursen, TA; Setton, LA(2001).”A finite-deformation, anisotropic, biphasic finite element model of cell-matrix interactions in the intervertebral disc” American Society of Mechanical Engineerings, Bioengineering Division (Publication) BED.50: 799- 800  More info
  • LeRoux, MA; Upton, ML; Laursen, TA; Setton, LA(2001).”Biphasic finite element modeling of tear effects on the mechanics of the meniscus” American Society of Mechanical Engineerings, Bioengineering Division (Publication) BED.50: 851- 852  More info
  • Meng, XN; LeRoux, MA; Setton, LA; Laursen, TA(2001).”Biphasic finite element formulation for modeling nonlinear response of articular cartilage to torsion” American Society of Mechanical Engineerings, Bioengineering Division (Publication) BED.50: 549- 550  More info
  • Baer, AE; Setton, LA(2000).”The micromechanical environment of intervertebral disc cells: effect of matrix anisotropy and cell geometry predicted by a linear model.” Journal of Biomechanical Engineering.122(3): 245- 251  More info
  • LeRoux, MA; Arokoski, J; Vail, TP; Guilak, F; Hyttinen, MM; Kiviranta, I; Setton, LA(2000).”Simultaneous changes in the mechanical properties, quantitative collagen organization, and proteoglycan concentration of articular cartilage following canine meniscectomy.” Journal of Orthopaedic Research.18(3): 383- 392  More info
  • Elliott, DM; Setton, LA(2000).”A linear material model for fiber-induced anisotropy of the anulus fibrosus.” Journal of Biomechanical Engineering.122(2): 173- 179  More info
  • Lindhorst, E; Vail, TP; Guilak, F; Wang, H; Setton, LA; Vilim, V; Kraus, VB(2000).”Longitudinal characterization of synovial fluid biomarkers in the canine meniscectomy model of osteoarthritis.” Journal of Orthopaedic Research.18(2): 269- 280  More info
  • Elliott, DM; Setton, LA(2000).”Erratum: A linear material model for fiber-induced anisotropy of the anulus fibrosus (Journal of Biochemical Engineering 122 (173-179))” Journal of Biomechanical Engineering.122(4): 461-  More info
  • Guilak, F; Ting-Beall, HP; Baer, AE; Trickey, WR; Erickson, GR; Setton, LA(1999).”Viscoelastic properties of intervertebral disc cells. Identification of two biomechanically distinct cell populations.” Spine.24(23): 2475- 2483  More info
  • LeRoux, MA; Guilak, F; Setton, LA(1999).”Compressive and shear properties of alginate gel: effects of sodium ions and alginate concentration.” Journal of Biomedical Materials Research.47(1): 46- 53 More info
  • Setton, LA; Guilak, F; Hsu, EW; Vail, TP(1999).”Biomechanical factors in tissue engineered meniscal repair.” Clinical Orthopaedics and Related Research ®.(367 Suppl): S254- S272  More info
  • Elliott, DM; Guilak, F; Vail, TP; Wang, JY; Setton, LA(1999).”Tensile properties of articular cartilage are altered by meniscectomy in a canine model of osteoarthritis.” Journal of Orthopaedic Research.17(4): 503- 508  More info
  • Hsu, EW; Setton, LA(1999).”Diffusion tensor microscopy of the intervertebral disc anulus fibrosus.” Magnetic Resonance in Medicine.41(5): 992- 999  More info
  • Narmoneva, DA; Wang, JY; Setton, LA(1999).”Nonuniform swelling-induced residual strains in articular cartilage.” Journal of Biomechanics.32(4): 401- 408  More info
  • Setton, LA; Elliott, DM; Mow, VC(1999).”Altered mechanics of cartilage with osteoarthritis: human osteoarthritis and an experimental model of joint degeneration.” Osteoarthritis and Cartilage.7(1): 2- 14  More info
  • Baer, AE; Wang, JY; Setton, LA(1999).”Mechanical properties of matrix synthesized by intervertebral disc cells in an alginate culture system” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.42: 119- 120  More info
  • Elliott, DM; Setton, LA(1999).”Direct measurement of a complete set of orthotropic material properties for the human anulus fibrosus in tension” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.42: 75- 76  More info
  • Guilak, F; Ting-Beall, HP; Baer, AE; Erickson, GR; Jones, WR; Pearsall, RL; Setton, LA(1999).”Identification of two biomechanically distinct cell populations in the intervertebral disc” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.42: 337- 338 More info
  • Hsu, EW; Setton, LA(1999).”Diffusion tensor microscopy of the intervertebral disc anulus fibrosus” Magnetic Resonance in Medicine.41(5): 992- 999  More info
  • Narmoneva, DA; Wang, JY; Setton, LA(1999).”New method for determination of the tensile modulus of articular cartilage in situ in a free-swelling configuration” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.43: 31- 32  More info
  • SETTON, L(1999).”Altered mechanics of cartilage with osteoarthritis : human osteoarthritis and an experimental model of joint degeneration” Osteoarthritis Cartilage.7: 2- 14  More info
  • Setton, LA; Baer, AE; Wang, JY; Kraus, VB(1999).”Biosynthesis of intervertebral disc matrix in vitro” Annual International Conference of the IEEE Engineering in Medicine and Biology – Proceedings.2: 1325-  More info
  • Setton, LA; Perry, CH; Elliott, DM; Wyland, DJ; LeRoux, MA; Guilak, F; Vail, TP(1999).”Anisotropic properties of the healing meniscus in tension” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.42: 73- 74  More info
  • Setton, LA; Perry, CH; LeRoux, MA; Wang, JY; Howell, DS; Cheung, HS(1999).”Altered mechanics of tibial cartilage following joint immobilization in a canine model” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.42: 71- 72  More info
  • Iatridis, JC; Setton, LA; Foster, RJ; Rawlins, BA; Weidenbaum, M; Mow, VC(1998).”Degeneration affects the anisotropic and nonlinear behaviors of human anulus fibrosus in compression.” Journal of Biomechanics.31(6): 535- 544  More info
  • Setton, LA; Tohyama, H; Mow, VC(1998).”Swelling and curling behaviors of articular cartilage.” Journal of Biomechanical Engineering.120(3): 355- 361  More info
  • Iatridis, JC; Setton, LA; Weidenbaum, M; Mow, VC(1997).”The viscoelastic behavior of the non-degenerate human lumbar nucleus pulposus in shear.” Journal of Biomechanics.30(10): 1005- 1013 More info
  • Iatridis, JC; Setton, LA; Weidenbaum, M; Mow, VC(1997).”Alterations in the mechanical behavior of the human lumbar nucleus pulposus with degeneration and aging.” Journal of Orthopaedic Research.15(2): 318- 322  More info
  • Setton, LA; Mow, VC; Müller, FJ; Pita, JC; Howell, DS(1997).”Mechanical behavior and biochemical composition of canine knee cartilage following periods of joint disuse and disuse with remobilization.” Osteoarthritis and Cartilage.5(1): 1- 16  More info
  • Elliott, DM; LeRoux, MA; Laursen, TA; Setton, LA(1997).”Formulation of a continuum anisotropic model for the anulus fibrosus in tension” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.36: 165- 166  More info
  • Narmoneva, DA; Wang, JY; Patel, SS; Howell, DS; Setton, LA(1997).”Altered swelling-induced strain fields in articular cartilage following periods of immobilization” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.36: 125- 126  More info
  • Iatridis, JC; Weidenbaum, M; Setton, LA; Mow, VC(1996).”Is the nucleus pulposus a solid or a fluid? Mechanical behaviors of the nucleus pulposus of the human intervertebral disc.” Spine.21(10): 1174- 1184  More info
  • Ebara, S; Iatridis, JC; Setton, LA; Foster, RJ; Mow, VC; Weidenbaum, M(1996).”Tensile properties of nondegenerate human lumbar anulus fibrosus.” Spine.21(4): 452- 461  More info
  • Elliott, DM; Setton, LA; Shah, MP; Vail, TP; Guilak, F(1996).”Effects of meniscectomy on the tensile properties of articular cartilage” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.33: 247- 248  More info
  • Weidenbaum, M; Iatridis, JC; Setton, LA; Foster, RJ; Mow, VC(1996).”Mechanical behavior of the intervertebral disk and the effects of degeneration” LOW BACK PAIN: A SCIENTIFIC AND CLINICAL OVERVIEW.: 557- 582  More info
  • Acaroglu, ER; Iatridis, JC; Setton, LA; Foster, RJ; Mow, VC; Weidenbaum, M(1995).”Degeneration and aging affect the tensile behavior of human lumbar anulus fibrosus.” Spine.20(24): 2690- 2701 More info
  • Setton, LA; Mow, VC; Howell, DS(1995).”Mechanical behavior of articular cartilage in shear is altered by transection of the anterior cruciate ligament.” Journal of Orthopaedic Research.13(4): 473- 482 More info
  • Grumbles, RM; Howell, DS; Howard, GA; Roos, BA; Setton, LA; Mow, VC; Ratcliffe, A; Muller, FJ; Altman, RD(1995).”Cartilage metalloproteases in disuse atrophy.” The Journal of rheumatology. Supplement.43: 146- 148  More info
  • Iatridis, JC; Setton, LA; Foster, RJ; Rawlins, BA; Weidenbaum, M; Mow, VC(1995).”Human anulus fibrosus behaves nonlinearly and isotropically in finite deformation confined compression” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.29: 251- 252  More info
  • McCutchen, CW; Setton, LA; Zhu, W; Mow, VC(1995).”Comment on the `Biphasic poroviscoelastic behavior of articular cartilage: role of the surface zone in governing the compressive behavior'” J. Biomech. (UK).28(4): 479, 481  More info
  • Setton, LA; Zhu, W; Mow, VC(1995).”Authors’ response” Journal of Biomechanics.28(4): 481-  More info
  • Setton, LA; Mow, VC(1995).”Contributions of flow-dependent and flow-independent viscoelasticity to the behavior of articular cartilage in oscillatory compression” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.29: 307- 308  More info
  • Müller, FJ; Setton, LA; Manicourt, DH; Mow, VC; Howell, DS; Pita, JC(1994).”Centrifugal and biochemical comparison of proteoglycan aggregates from articular cartilage in experimental joint disuse and joint instability.” Journal of Orthopaedic Research.12(4): 498- 508  More info
  • Setton, LA; Mow, VC; Müller, FJ; Pita, JC; Howell, DS(1994).”Mechanical properties of canine articular cartilage are significantly altered following transection of the anterior cruciate ligament.” Journal of Orthopaedic Research.12(4): 451- 463  More info
  • Best, BA; Guilak, F; Setton, LA; Zhu, W; Saed-Nejad, F; Ratcliffe, A; Weidenbaum, M; Mow, VC(1994).”Compressive mechanical properties of the human anulus fibrosus and their relationship to biochemical composition.” Spine.19(2): 212- 221  More info
  • Iatridis, JC; Setton, LA; Weidenbaum, M; Mow, VC(1994).”Determination of a relaxation spectrum to evaluate the viscoelastic behavior of the nucleus pulposus in shear” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.28: 317- 318  More info
  • MOW, V; BACHRACH, N; SETTON, L; GUILAK, F(1994).”STRESS, STRAIN, PRESSURE AND FLOW-FIELDS IN ARTICULAR-CARTILAGE AND CHONDROCYTES” CELL MECHANICS AND CELLULAR ENGINEERING.: 345- 379  More info
  • Setton, LA; Tohyama, H; Lai, WM; Guilak, F; Mow, VC(1994).”Experimental measurement of the in vitro curling behavior of articular cartilage” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.28: 135- 136  More info
  • Setton, LA; Zhu, W; Mow, VC(1993).”The biphasic poroviscoelastic behavior of articular cartilage: role of the surface zone in governing the compressive behavior.” Journal of Biomechanics.26(4-5): 581- 592  More info
  • Setton, LA; Zhu, W; Weidenbaum, M; Ratcliffe, A; Mow, VC(1993).”Compressive properties of the cartilaginous end-plate of the baboon lumbar spine.” Journal of Orthopaedic Research.11(2): 228- 239 More info
  • Setton, LA; Lai, WM; Mow, VC(1993).”Swelling-induced residual stress and the mechanism of curling in articular cartilage in vitro” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.26: 59- 62  More info
  • Setton, LA; Mow, VC; Muller, FJ; Pita, JC; Howell, DS(1993).”Altered structure-function relationships for articular cartilage in human osteoarthritis and an experimental canine model.” Agents and Actions Supplements.39: 27- 48  More info
  • Setton, LA; Gu, WY; Lai, WM; Mow, VC(1992).”Pre-stress in articular cartilage due to internal swelling pressure” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.22: 485- 488  More info
  • Setton, LA; Mow, VC(1992).”Generalized biphasic poroviscoelastic model for articular cartilage: Theory and experiments” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.22: 589- 592  More info
  • Lai, WM; Gu, W; Setton, LA; Mow, VC(1991).”Conditional equivalence of chemical loading and mechanical loading on articular cartilage” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.20: 481- 484  More info